The full name of this project, where our new company geneXplain is a partner, is "Systems biology-driven approach to unravel and revert the mechanisms responsible for poor immune responses in the elderly". Its strategic objective is to draw on a Systems Biology-driven approach to understand the molecular processes affected during immunosenescence, in order to derive (i) global mathematical models describing the involved processes, (ii) a holistic model for flu infections in young and elderly, and (iii) strategies to overcome these processes to establish immune interventions tailored for the elderly.
GERONTOSHIELD is a collaborative project funded by the German Federal Ministry of Education and Research (BMBF) in the funding program "Systems Biology for Health in the Old Age – GerontoSys2", coordinated by Prof. Dr. Carlos Guzmán, Helmholtz Centre for Infection Research (HZI) in Braunschweig, Germany. The 6 participants of the consortium are from Braunschweig, Jena, Martinsried, Regensburg, Tübingen, and Wolfenbüttel.
The contract period is from February 1st, 2011 - January 31st, 2014.