TBX1_d1

 

 

 

 

A

C

G

T

 

Name

TBX1

1

6790

23

978

1855

 

TF group

TBX

2

1576

1003

6165

925

 

Polypeptide used

DBD

3

9

4

7564

26

 

Ligand sequence

TACGGA40NGGC

4

9

113

64

7491

 

Batch of SELEX experiment

AI

5

7

11

7557

15

 

Seed sequence

AGGTGTGAAAAAAGGTGTGA

6

58

414

37

7446

 

Hamming distance of sequences to seed

3

7

26

252

5703

1968

 

SELEX cycle

4

8

7584

7

5

0

 

Number of repeats

dimeric

9

7308

30

933

433

 

Comment

 

10

7158

349

937

1116

 

Representative matrix

yes

11

6258

671

830

2520

 

 

 

12

6787

1566

1036

1724

 

 

 

13

7379

3

302

239

 

 

 

14

1978

914

6353

1298

 

 

 

15

8

12

7526

49

 

 

 

16

392

416

31

7267

 

 

 

17

5

0

7581

0

 

 

 

18

353

299

18

7570

 

Source:

 

19

54

173

7545

1622

 

Jolma et al., Cell 152:327-339 (2013); PubMed 23332764

20

7565

26

32

7

 

 

 

 

 

 

 

 

 

 

 

 

TBX1_d2

 

 

 

 

A

C

G

T

 

Name

TBX1

1

6440

21

152

177

 

TF group

TBX

2

734

49

10018

94

 

Polypeptide used

DBD

3

5

4

9639

8

 

Ligand sequence

TACGGA40NGGC

4

22

50

167

8767

 

Batch of SELEX experiment

AI

5

2

1

10319

0

 

Seed sequence

AGGTGTGAAWTTCACACCT

6

41

184

51

8790

 

Hamming distance of sequences to seed

2

7

54

52

10256

74

 

SELEX cycle

4

8

6441

1

12

0

 

Number of repeats

dimeric

9

6108

550

32

548

 

Comment

 

10

2704

23

46

5169

 

Representative matrix

no

11

2694

46

171

6305

 

 

 

12

5

1

19

8744

 

 

 

13

193

6270

157

15

 

 

 

14

6163

30

280

99

 

 

 

15

2

6264

6

5

 

 

 

16

6551

22

30

0

 

 

 

17

4

6089

19

2

 

Source:

 

18

28

5643

149

786

 

Jolma et al., Cell 152:327-339 (2013); PubMed 23332764

19

27

279

33

8877

 

 

 

 

 

 

 

 

 

 

 

 

TBX1_m1

 

 

 

 

A

C

G

T

 

Name

TBX1

1

11931

113

1007

564

 

TF group

TBX

2

1560

711

11931

669

 

Polypeptide used

DBD

3

0

0

11931

0

 

Ligand sequence

TACGGA40NGGC

4

28

214

141

11931

 

Batch of SELEX experiment

AI

5

0

5

11931

0

 

Seed sequence

AGGTGTGA

6

142

613

109

11931

 

Hamming distance of sequences to seed

1

7

141

720

11931

1039

 

SELEX cycle

4

8

11931

33

18

0

 

Number of repeats

monomeric

 

 

 

 

 

 

Comment

 

 

 

 

 

 

 

Representative matrix

no

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Source:

 

 

 

 

 

 

 

Jolma et al., Cell 152:327-339 (2013); PubMed 23332764

 

 

 

 

 

 

 

 

 

TBX1_d3

 

 

 

 

A

C

G

T

 

Name

TBX1

1

229

1869

1253

9297

 

TF group

TBX

2

233

687

83

11232

 

Polypeptide used

DBD

3

0

0

11

11922

 

Ligand sequence

TACGGA40NGGC

4

874

7686

661

10

 

Batch of SELEX experiment

AI

5

8701

3

2626

1

 

Seed sequence

TYTCACACCTNNNAGGTGTGARA

6

14

8413

22

8

 

Hamming distance of sequences to seed

2

7

8717

7

74

9

 

SELEX cycle

4

8

5

8399

7

3

 

Number of repeats

dimeric

9

106

8270

4

641

 

Comment

 

10

99

381

612

12029

 

Representative matrix

no

11

673

4775

684

3777

 

 

 

12

4794

458

504

4150

 

 

 

13

4062

351

6518

6

 

 

 

14

8908

44

47

8

 

 

 

15

613

99

9778

3981

 

 

 

16

3

0

13786

3

 

 

 

17

41

71

252

11972

 

 

 

18

7

5

13766

5

 

 

 

19

100

2654

33

8586

 

 

 

20

18

534

13241

335

 

Source:

 

21

8949

104

20

12

 

Jolma et al., Cell 152:327-339 (2013); PubMed 23332764

22

4221

36

7128

460

 

 

 

 

 

 

 

 

 

 

 

 

TBX1_d4

 

 

 

 

A

C

G

T

 

Name

TBX1

1

730

472

767

11227

 

TF group

TBX

2

9

7

56

12141

 

Polypeptide used

DBD

3

329

7981

573

4

 

Ligand sequence

TACGGA40NGGC

4

8622

2

178

216

 

Batch of SELEX experiment

AI

5

2

8154

20

3

 

Seed sequence

YTCACACCTNNAGGTGTGAR

6

8518

10

349

22

 

Hamming distance of sequences to seed

2

7

8

8298

22

5

 

SELEX cycle

4

8

1720

7767

108

636

 

Number of repeats

dimeric

9

182

484

296

11588

 

Comment

 

10

3223

4316

1047

126

 

Representative matrix

yes

11

2692

2274

257

4777

 

 

 

12

7009

1799

794

83

 

 

 

13

542

2525

9882

210

 

 

 

14

6

82

13640

1

 

 

 

15

16

136

150

11750

 

 

 

16

0

0

13953

1

 

 

 

17

243

128

93

11623

 

 

 

18

6

135

13381

688

 

Source:

 

19

8730

42

24

14

 

Jolma et al., Cell 152:327-339 (2013); PubMed 23332764

20

5372

97

4683

1455