This project, "Epigenetic mechanisms underlying predisposition to metabolic syndrome-associated diseases", aims at gaining a better insight on the etiology of different disease conditions such as obesity or type-2 diabetes by investigating the intertwining of genetic, epigenetic and environmental factors. This innovative project is expected to pave the way to new preventive and therapeutic approaches at the individual level and for ameliorating the quality of life at the general population level.

Our company geneXplain contributes to the project its expertise in promoter analysis and its platform, which will be adapted to the specific needs of the project partners. At the end, a novel integrative view on the regulatory network comprising genetic and epigenetics influences will be provided.

EPIMETAB is a collaborative project funded by the German Federal Ministry of Education and Research (BMBF) in a Joint Transnational Call 2011 for "Integrated Research on Genomics and Pathophysiology of the Metabolic Syndrome and the Diseases arising from it". It is coordinated by Prof. Dr. Pierre Fafournoux, Institut National de la Recherche Agronomique in Saint Genès Champanelle, France. The 4 participants of the consortium are from France (Saint Genès Champanelle and Paris), Spain (Barcelona), and Germany (Wolfenbüttel). The contract period is from April 1st, 2012, to March 31st, 2015.

You may learn more about the geneXplain contribution to EPIMETAB here.